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11th Global Healthcare and Fitness Summit

San Francisco, USA

Dr. K Zaman

Dr. K Zaman

International Centre for Diarrheal Disease Research, Bangladesh

Title: Epidemiology and prevention of Hepatitis E virus (HEV) infection and diseases

Biography

Biography: Dr. K Zaman

Abstract

Hepatitis E virus (HEV) infection is a major cause of liver inflammation worldwide and is the commonest cause of acute
liver disease in South Asia, including Bangladesh. It is the leading cause of enteric hepatitis illness both in epidemic and sporadic cases. Globally prevalence rates of HEV infection and diseases vary by region, population and circulating genotypes, with unexpectedly high in some developed countries. HEV spreads via contaminated drinking water and food. Pregnant woman and their babies bear the greatest burden from HEV. Mortality rate among pregnant women infected with HEV has been estimated to be 5-25%. There are currently no effective medicines to prevent or treat HEV infection. So efforts to reduce the numbers of HEV infections in pregnancy in the South Asia region could have a major global impact. A newly developed vaccine manufactured by Innovax (China) is safe and effective. We have recently started a study to determine the effectiveness of HEV vaccine among 20,000 non-pregnant women in preventing HEV disease during pregnancy in rural Bangladesh.
Detailed epidemiology and prevention of HEV infection and diseases will be presented.