Day 2 :
University of Siena | Italy
Time : 09:00-09:40
Domenico Mastrangelo has completed his degree in Medicine and Surgery on October 26th, 1979, at the age of 24. He then specialized in hematology in 1983, Oncology in 1987, Clinical Pharmacology in 1990, Ophthalmology in 2010. His experience is in the fields of hematological/oncological epidemiology and laboratory, cell biology molecular biology. He published more than 100 papers in reputed scientific journals, including chapters in highly reputed scientific books, in the fields of ocular oncology clinical oncology, cancer cell biology, and hematology. Presently he is a Senior Scientist at the Department of Medical, Surgical, and Neurological Sciences of the University of Siena, Italy.
The selective anticancer properties of Vitamin C are known since at least four decades. However, only recently in vitro studies have shown that Vitamin C, in high enough concentrations, can efficiently and selectively kill a number of different human tumor cell lines, and these data have been confirmed in experimental animal tumor models.
The first human clinical trials, revealed that high doses of Vitamin C administered by intravenous injection, are not only very well tolerated, but substantially improve the quality of life of patients with clinically advanced cancer. However the clinical evidence of the effectiveness of Vitamin C in fighting off cancer, is still controversial.
The present chapter outlines the importance of Vitamin C for a number of physiologic functions, within the human body and shows that there is a solid rationale for its use in the routine treatment of cancer, either alone or in combination with conventional treatment.
Oregon Health & Science University | USA
Time : 09:40-10:20
Gail M. Wolf is a nurse educator and reading researcher who works at Oregon Health & Science University. Wolf’s focus is on public health, leadership, and the connection between literacy skills, and health. Wolf’s research on early literacy shows the connection between early childhood literacy, later adult literacy, and living a productive, healthy life. Wolf has spent decades teaching preschool children to read. She has presented her work at the National Institute for Healthcare Advancement’s Health Literacy Conference in 2010, and 2013. Wolf is currently writing up her research results with bilingual, Latino teachers and First Grade Hispanic children on early biliteracy.
Statement of Problem: Poor early literacy can be viewed as a chronic disease process that is a public health concern. Data shows children’s failure to develop simple word decoding skills in early years is linked to future poor reading, school dropout teen pregnancy, low self-esteem, entrance into crime, and life-long poor health. Letter-sound knowledge is needed for word decoding development; however questions remain on what types of letter-sound knowledge help children decode simple words.
This study investigated the differences in mean number of consonant-vowel-consonant (CVC) words decoded between two groups of children, a letter-sound reading group and non-letter-sound reading group. Children aged 4 to 6 in both groups attempted to decode a variety of simple words such as tan, sit, hen, pig, dot, and fun.
Analysis determined word decoding differences existed between the two groups. The letter-sound reading group had a significantly higher mean in number of CVC words decoded compared to the non-letter-sound reading group. The study informs the teaching approaches needed to improve early decoding skills showing letter-sound reading ability is an important step for learning to decode simple consonant-vowel-consonant words. Further, promoting early literacy, promotes life-long health, well-being, and living a productive life.
- Wolf, G.M. (2016). Letter-sound reading: Teaching preschool children print-to-sound processing. Early Childhood Education Journal, 44(1), 11-19. doi: 10.1007/s10643-014-0685-y
- Wolf, G.M. (2014). Differences in Mean Number of Consonant-Vowel-Consonant Words Decoded between Letter-Sound Readers and Non Letter-Sound Readers. Open Journal of Nursing, 4, 409-450. doi: 10.4236/ojn.2014.46047
- Wolf, G. M. (2015). Selected to present at Oregon’s Statewide Head Start Early Childhood Specialist Conference: April 9, 2015, Redmond, Oregon at Eagle Crest Resort. Bend, Oregon. Presentation is dissemination of National Institute of Health (NIH) grant research data results of early literacy and impact on health.
- Wolf, G.M. (2013). Selected to present at National Institute of Healthcare Advancement’s (IHA) 10th Annual Health Literacy Conference. Irving, California. Poster on Innovations in Reading Instruction the connection between early literacy and living a productive, health life.
- Wolf, G.M. (1998). The three ingredient reading program: You can teach your child to read. Mesa, AZ: Blue Bird Publishing. [2nd edition in process, 2017].
St. Elizabeth University of Health and Social Work | Slovakia
Time : 10:20-11:00
Miron Sramka studied at Faculty of Medicine of Charl´s University in Prague. He worked as research worker at Institute of Pharmacology of Czechoslovak Academy of Science. He worked as Department head at Department of Stereotactic and functional Neurosurgery from Faculty of Medicine Comenius University, Bratislava. Miron Sramka worked as a Professor at University Public Health and Social Work St. Elisabeth; He acts as head of Clinic of Stereotactic Radiosurgery. He is the member of the European executive committee for stereotactic and functional neurosurgery. New diagnostic methods: Spinal cord stereotaxy, Transplantation of brain tissue by the Parkinsonism and Hungtington’s chorea, Method of MR guided stereotaxy, Stereotactic radiosurgery of melanoma of eye, Virtual 3D printing by radiosurgical operation of head in collaboration with Dr. Ruzicky (Dean of the Faculty of Informatics PEU) showed the possibilities of 3D printing used in order to decide which modality surgery is most appropriate for the patient in order to maintain the highest quality of life after surgery.
A new Virtual Reality device has given new possibilities for a 3D imagination in the planning and treatment of various diseases. 3D printing method helps determine which surgery or modality radiation is optimal. 3D printing technology helps to make of prostheses, assistive devices, production of hearing aids, prostheses, nose, ears, eyes, teeth, breast reconstruction of bone substitutes. Method of 3D printing cells (bioprinting) also helps in treating skin injuries and regenerative medicine in which the patient's stem cells form filling printers. We used the 3D printers especially for tumor irradiation near the critical structures for better imagination during the planning treatment at radiosurgery. In this case we can better visualize for neurosurgeons some 3D objects of interest. The history of Virtual Reality (VR) began in the 90s of the last century. Technology Research Company Gartner forecasted mass use of VR after 2010. Company Oculus Rift designed prototype Oculus Rift DK in 2010 and later in 2013 Oculus Rift VR. Company HTC with Valve Corporation announced their virtual reality headset HTC Vive in 2015 and was distributed in 2016, which is the second most widely used VR model today.
Both models Oculus Rift VR and HTC Vive we have successfully implemented in the projects focused on the mapping natural curiosities. The experiences of these VR devices we now apply for neurosurgical planning in which we use software system TomoCon and our NeuroVR system. We used 3D printing in neuro-oncology with radiosurgical planning performance. With the 3D model printing, we increased the accuracy of the therapeutic dose and at the same time we calculated the lowest dose to risk structures. 3D printing method helps determine which modality radiation is optimal. For operations of the eye’s melanoma we created a set of 3D physical models of the eye and tumour.
- Šramka M et al. (2016) The possibilities of 3D printing in Surgery. Health in social work. 3:15-20.
- Šramka M, Ružický E (2016) Possibilities in 3D Printing by Radiosurgical Operations. Journal of Biosciences and Medicines, 4:18-22.
- Furdova A, Sramka M, Chorvath M, Kralik G, Krasnik V, Krcova I, Waczulikova I (2014) Stereotactic radiosurgery in intraocular malignant melanoma – retrospective study. Neuroendocrinol Lett 1:28–36.
- Ruzicky E, Šramka M (1995) Mathematical methods using CT and MR images for stereotactic neurosurgery. Molecular and Chemical Neuropathology 25:247–254.
- Ružický E, (2015) Formalization of user interaction with virtual expert resource of knowledge type via ontological modeling. Information technology applications. 1:33-43.