Ahamad Kanaan A. Uwaydah
Zayed Hospital, Abu Dhabi, UAE
Title: CANDIDEMIA: A REVIEW OVER 5 YEARS AT A 300 BEDS MILITARY HOSPITAL (SERVING MILITARY PERSONNEL AND THEIR FAMILIES) IN THE UNITED ARAB EMIRATES.
Biography
Biography: Ahamad Kanaan A. Uwaydah
Abstract
Background: Candida species(C. Species) are increasigly isolated from blood cultures (1) being the fourth most common blood culture isolate in recent years.
Material/methods: Retrospective review of the microbiology laboratoryrecords, for the period from 1st January 2010 till end of December 2014was carried out.
Results: Ninety three episodes were identified. C. parapsilosis was the most common isolate (30) followed by tropicalis (29) then albicans (16 ), and glabrata (12)
C. albicans, C. tropicalis and C. glabrata were sensitive to Fluconazole in100%, 100% and 91.6%, respectively.
C. parapsilosis was sensitive to fluconazole in only 21.4%(6 isolates) and intermediate in (78.6%) 22 isolates.
Central venous access was the documented source of candidemia in 39.7% (37 episodes).
C parapsilosis accounted for (16) of them followed by albicans (10 ), tropicalis (9) and kruseii (2)
Candidemia trends changed during 2014 as new species never isolated before emerged, such as Krusei( 2), Guilliermondii (1), Lusitanii (1) and others( 2).
Conclusions: Non albicans candida has outnumbered albicans as blood stream isolates in the past 5 yearswith candida parapsillosis being the most prevalent isolate. In view of the unusual sensitivity pattern of C.parapsillosis and the emergence of new C.species prospective studies are required to evaluate candidemia riskfactors, especially central lines use and antifungal treatment patterns in order to formulate appropriate preventive and therapeutic recommendations.